Luba Markewycz was a teacher by profession and taught in the Chicago Public School system for over thirty years. She also worked in several leadership roles at the Ukrainian Institute of Modern Art (UIMA) in Chicago. Markewycz served as UIMA president, vice president, and a board member, a member of the art committee, and chair of the education committee. As a teacher, she was interested in children's art and how it reflects life from a child’s perspective.
In 2008, Markewycz became the project director for the exhibit "Holodomor through the Eyes of a Child." She believed the tragic event of the Holodomor in the 1930s was important to keep in the forefront of collective memory, not only of Ukrainians but the entire world. Determining that children’s art would be a powerful medium through which to inform people of this holocaust, Markewycz traveled to several schools and regional centers throughout Ukraine, and asked children (grades 6 – 11) to learn of and represent their understanding of the Holodomor. The process culminated in the exhibit, composed of 400 works of art from 12 cities and over 20 schools. The second Ukrainian student exhibit Markewycz commissioned was "Literature Art,” and she is currently working on the exhibit, "The Vanishing World of My Grandparents and What Treasures They Would Like to Leave Us."
Also a photographer, Markewycz traveled to Chernobyl twice after the 1986 nuclear disaster and has exhibited photography from these experiences in Chicago, Houston, L’viv, Kyjv, and other small cities in Ukraine. Her other photo exhibits that have been showcased in the United States and Ukraine include "The Lovely Cafes of L'viv" and "My Impressions of Chicago.”
Markewycz also served a four year tenure as principal of the Ethnic School of Ukrainian Studies in Chicago. She taught English in the summer program at Ukrainian Catholic University (UCU), and gave seminars on Shakespeare at UCU and Ivan Franko University in L'viv.